![](https://static.wixstatic.com/media/11062b_57eee0be03fd4f26b8819bc60ef5b3c9f000.jpg/v1/fill/w_288,h_162,al_c,q_80,usm_0.66_1.00_0.01,blur_2,enc_auto/11062b_57eee0be03fd4f26b8819bc60ef5b3c9f000.jpg)
![Balanced Objects](https://static.wixstatic.com/media/11062b_68de6b1a67ae45fa9ca762e900c7f2d0~mv2.jpg/v1/fill/w_96,h_67,al_c,q_80,usm_0.66_1.00_0.01,blur_2,enc_auto/11062b_68de6b1a67ae45fa9ca762e900c7f2d0~mv2.jpg)
Our Programs
MD2 Biosciences is a biopharmaceutical company focused on discovering, developing, and commercializing therapeutics in oncology, and pulmonary fibrosis. We are pursuing product candidates with a solid scientific rationale to address a high unmet need in oncology and pulmonary fibrosis and an opportunity to develop best-in-class or first-in-class programs.
![Surgical Lights](https://static.wixstatic.com/media/11062b_4e582f28c46b44929498d250c4626283~mv2.jpeg/v1/fill/w_378,h_283,al_c,q_80,usm_0.66_1.00_0.01,enc_auto/Surgical%20Lights.jpeg)
01
Colorectal Cancer
Approximately 90% of sporadic CRCs contain mutations in components of the Wnt/β-catenin signaling pathway. These mutations are found in the earliest neoplasms, suggesting that this pathway is a critical gatekeeper to prevent colorectal carcinogenesis.
02
Gastrointestinal Stromal Tumors
The wnt/β-catenin signaling pathway is essential in the malignant transformation of GIST and thus overexpressed in GIST.
![Image by National Cancer Institute](https://static.wixstatic.com/media/nsplsh_4c6e764345585177432d6f~mv2.jpg/v1/fill/w_71,h_71,al_c,q_80,usm_0.66_1.00_0.01,blur_2,enc_auto/Image%20by%20National%20Cancer%20Institute.jpg)
![Brain Sketch](https://static.wixstatic.com/media/65caf121bc1f49029c25168f0073f026.jpg/v1/fill/w_71,h_71,al_c,q_80,usm_0.66_1.00_0.01,blur_2,enc_auto/Brain%20Sketch.jpg)
03
Brain Cancer
β-catenin is known to induce transcriptional expression of PD-L1 to promote glioma immune invasion.
04
Pulmonary Fibrosis
Aberrant activation of Wnt/β-catenin signaling occurs in all fibrotic lung diseases and could be a potential target for novel treatment approaches.
![Lungs Sketch](https://static.wixstatic.com/media/a02a7d9e6ea54e0985c11cc536f79e83.jpg/v1/fill/w_95,h_66,al_c,q_80,usm_0.66_1.00_0.01,blur_2,enc_auto/Lungs%20Sketch.jpg)